Regenerative Medicine for Parkinson’s Disease

17 June 2021

Event Name: 

ACTRIS Cell Therapy Lecture Series: Regenerative Medicine for Parkinson’s Disease

Date: 

17 June 2021

Time: 

12 noon to 1pm

Synopsis: 

Parkinson’s Disease (PD) is a neurodegenerative disease affecting millions of predominantly elderly individuals worldwide. Despite intensive efforts devoted to drug discovery, the disease remains incurable.

Pathologically, PD is characterised by the loss of a rather selective population of dopamine-producing neurons in a circumscribed region of the brain, which makes cell-based therapy a feasible option.

Proof-of-concept studies to support this approach have been conducted as early as the 1970s. This was followed by several high-profile clinical trials using foetal mesencephalic tissue as a source for transplantation, which gave mixed results. More recently, investigators have turned to induced pluripotent stem cell (iPS) technology to derive dopaminergic neurons for grafting. Notably, human trials for PD with iPS-derived cells are currently ongoing in Japan. As with every clinical trial, hope and risk are interwoven in tandem.

Join this webinar to find out what are the ongoing efforts in cell-based therapy for PD and get a brief update on Singapore’s efforts in this space that may impact the future of regenerative medicine.

Speaker

Prof Lim Kah Leong
Professor and Vice Dean (Research),
President’s Chair in Translational Neuroscience
Lee Kong Chian School of Medicine, NTU

 

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